New study puts gutmicrobiome at the center of Parkinson's disease pathogenesis NatureComms
Each subject provided one stool sample at one time point; hence each data point represents a unique individual. Each sample was measured and analyzed once. Stool samples were collected at home. Nearly all subjects used the DNA Genotek OMNIgene GUT Collection kit. Five subjects used Fisher Scientific DNA/RNA-free BD BBL Sterile/Media-free Swabs. Collection method was included as a technical covariate in analyses. Upon receipt in the lab, samples were stored in −20 °C freezer.
, with one difference: as our sequencing protocol did not include PCR amplification step, we did not remove duplicated sequences, as these may be actual biological overrepresentation.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
A neural circuit for the suppression of feeding under persistent pain - Nature MetabolismChronic pain is often accompanied by decreased appetite. The authors uncover the neuronal circuits that lead to reduced feeding in a mouse model of persistent pain, which involves cortical-to-hypothalamic glutamatergic signalling.
Read more »
Molecular basis for selective activation of DREADD-based chemogenetics - NatureThe mechanism of action of muscarinic receptor-based DREADDs, important chemogenetic tools in neuroscience and cellular signalling research, are described in molecular detail.
Read more »
Structure-based design of bitopic ligands for the µ-opioid receptor - NatureNature - Structure-based design of bitopic ligands for the µ-opioid receptor
Read more »
Government ‘failing to keep promises’ on restoring nature – Wildlife TrustsThe Government has come under fire for its record of “failing to keep promises” on the environment ahead of global talks aimed at reversing nature losses.
Read more »
Expanding freedom to roam to woods could ‘unlock’ nature for poor communitiesThe poorest communities would have access to nature an average of just 20 minutes’ walk away if the freedom to roam included woodlands, campaigners claim. They're calling on the government to add woodland to the law.
Read more »
Time for women-centred gynaecology - Nature Reviews UrologyAlthough gynaecology is a specialty responsible for women’s health, the field was historically male-dominated and its science remains biased towards male perceptions of women’s health. In light of the changing social climate in our society and the changing gender composition of the specialty, a number of steps can be taken to make gynaecology more women-centred.
Read more »