A large study reveals an increased risk for adverse cardiovascular events but not for liver disease progression in adults with MASLD disease and HIV infection.
compared with MASLD alone. However, the incidence of major adverse cardiovascular events is significantly increased among patients with MASLD and HIV , a large study suggested.MASLD is highly prevalent in people living with HIV , but the impact of HIV on liver and cardiovascular disease outcomes in people with MASLD remains unclear.
To investigate, researchers created a propensity score-matched cohort of veterans with noncirrhotic MASLD, with and without HIV . They evaluated the incidence of cirrhosis, HCC, and MACE, as well as overall survival, among the two groups. They also assessed these outcomes in MASLD patients with HIV on the basis of whether they were on antiretroviral therapy .During a median follow-up of 10.4 years in the MASLD with HIV group and 11.8 years in the MASLD-only group, the overall incidence of cirrhosis and HCC was similar in MASLD with vs without HIV .
HIV Disease HIV Liver Disease Hepatic Impairment Liver Biliary Disease Gallbladder Disease Hepatocellular Carcinoma HCC - Hepatocellular Carcinoma Liver Cancer HCC Hepatocellular Cancer Cancer Of The Liver Liver Carcinoma Carcinoma Of The Liver Metabolism Metabolic Cirrhosis California Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Cardiovascular Disease
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