Science, Space and Technology News 2024
A new study from Japan shows dopamine may help reduce Alzheimer’s disease symptoms by increasing neprilysin, an enzyme that dissolves harmful brain plaques. This finding, proven effective in mice, could transform treatment approaches if applicable to humans. Credit: SciTechDaily.com
This breakthrough in mice models offers potential for a new treatment approach if replicated in human trials, emphasizing the importance of dopamine in managing the disease and opening new avenues for research.A new way to combat Alzheimer’s disease has been discovered by Takaomi Saido and his team at the RIKEN Center for Brain Science in Japan.
In the new study, Saido’s team at RIKEN CBS focuses on the enzyme neprilysin because previous experiments showed that genetic manipulation that produces excess neprilysin in the brain—a process called upregulation—resulted in fewer beta-amyloid plaques and improved memory in mice.While genetically manipulating mice to produce neprilysin is useful experimentally, to treat people with the disease, we need a way to do it using medication.
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