Major Trial Finds MDMA-Assisted Therapy Is Effective for PTSD, Paving Way for FDA Approval

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Major Trial Finds MDMA-Assisted Therapy Is Effective for PTSD, Paving Way for FDA Approval
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The new study found that a combination of MDMA and psychotherapy was more effective at relieving PTSD symptoms when compared to standard therapy.

MDMA is short for 3,4-methylenedioxy-methamphetamine. It’s a synthetic drug with both stimulant and psychedelic effects. It’s been used historically as a recreational drug, going under the nicknames of Mollyillegal controlled substance by the U.S. federal government since the 1980s. But for decades, some psychologists and researchers have experimented with using MDMA as a way to boost the potency of talk therapy, particularly for PTSD.

in Nature Medicine in 2021. But the new study, unlike the first, was able to include a more diverse group of participants this time around, an important consideration for the approval of any new drug or therapy. Though not everyone seems responsive to MDMA-assisted therapy, the treatment could provide a valuable new option for people who haven’t responded to existing medications or therapy.

MAPS is proceeding with its application and plans to submit for formal FDA approval before the end of 2023. If successful, MDMA-assisted therapy could be available to the public as early as next year.

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