MacArthur Foundation awards $100M to outbreak surveillance network, a boost amid global health cuts

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MacArthur Foundation awards $100M to outbreak surveillance network, a boost amid global health cuts
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The MacArthur Foundation is awarding $100 million to a private pandemic prevention network across Africa, offering critical support to infectious disease surveillance at a time when governments are deprioritizing global health spending.

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Christian Happi poses for a photo inside the laboratory at the Institute of Genomics and Global Health, in Ede Southwestern, Nigeria, Nov. 17, 2025. Dr. Christian Happi, sits inside the laboratory at the Institute of Genomics and Global Health, in Ede Southwestern, Nigeria, Nov. 17, 2025. Dr. Christian Happi enters the laboratory at the Institute of Genomics and Global Health, in Ede Southwestern, Nigeria, Nov. 17, 2025. Dr. Christian Happi poses for a photo at the Institute of Genomics and Global Health in Ede southwestern, Nigeria, Nov. 17, 2025. FILE - Dr. Pardis Sabeti Professor, Center for Systems Biology and Department of Organismic and Evolutionary Biology Harvard speaks during the during the TIME 100 Summit, April 23, 2019, in New York. Dr. Christian Happi poses for a photo inside the laboratory at the Institute of Genomics and Global Health, in Ede Southwestern, Nigeria, Nov. 17, 2025. – The MacArthur Foundation is awarding $100 million to a private pandemic prevention network across Africa, offering critical support to infectious disease surveillance at a time when governments are reducing global health spending. It was announced Tuesday that Sentinel — a project that creates cost-effective pathogen detection tests, monitors outbreaks with real-time tracking tools and trains local scientists to carry out community-led responses — won theSentinel reports training more than 3,000 public health workers from 53 of Africa’s 54 countries. The award money will help expand its geographic reach over the next five years, creating a more robust system that can better alert local communities — and, in turn, the world — to previously undetected diseases. “This investment affirms that solutions to global health challenges can be led from Africa,” Sentinel co-director Christian Happi, who leads the Institute of Genomics and Global Health at Redeemer’s University in Nigeria, said in a statement. “Sentinel is about trust, collaboration, and building the systems that allow every country to respond swiftly and confidently to disease threats." With the MacArthur Foundation's recognition of an African initiative that is empowering public health officials from the bottom up, the heavyweight American philanthropy hopes to encourage similar investments from its peers. In the ten years since starting 100&Change with the issue-agnostic goal of driving philanthropy to pursue bolder endeavors and larger grants, an official said they’ve seen just that — as well as more concern for global health. “This grant is further wind in those sails, I'd say” said Chris Cardona, the managing director of Exploration, Discovery and Programs at the MacArthur Foundation."But given the scale of the challenge and the size of the funding gaps, there’s much more to be done.” “We are glad to shine that spotlight and to show the value for U.S. donors of funding internationally — especially to projects that are bridging and building capacity across countries like Sentinel is doing," he added.stop working with the World Health Organization“This work in Africa would be important because, as the U.S. and European nations pull out from support globally, we will have less visibility of what’s going on overseas," said Dr. Ali S. Khan, dean of the University of Nebraska Medical Center College of Public Health. Sentinel began as a collaboration between Happi’s lab and Dr. Pardis Sabeti’s lab at the Broad Institute in Cambridge, Massachusetts, on. Traveling into villages where the virus was spreading provided key insights they wouldn’t have had without deeply embedding in the community, according to Sabeti. They've now set out to provide those communities with the diagnostic technologies and professional connections necessary to identify, control and send early warnings about new threats. Sabeti said the award is “transformative” considering that public health is being “decimated” and the field faces “existential crises.” When the United States no longer supports other countries’ efforts to stop pandemics like it used to, she said, local frontline responders must be empowered. “By giving people in communities the information that they need, they end up becoming sentinels for an emerging outbreak,” Sabeti said. “And it’s really allowing every person on the planet to participate in stopping the next pandemic.” Former USAID Deputy Assistant Administrator for Global Health Nidhi Bouri said governments' budget cuts have highlighted the need for diversified funding streams. She emphasized that pandemic surveillance requires “continuous monitoring” and is “not something you can do half the time.” “There is a collective responsibility — but more so a collective interest globally — for a range of stakeholders to evaluate how they can support different investments with the shared goal of mitigating the spread of diseases across the globe,” Bouri said."Because it impacts everyone.”Associated Press coverage of philanthropy and nonprofits receives support through the AP’s collaboration with The Conversation US, with funding from Lilly Endowment Inc. The AP is solely responsible for this content. For all of AP’s philanthropy coverage, visit Copyright 2025 The Associated Press. All rights reserved. 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MacArthur Foundation awards $100M to outbreak surveillance network, a boost amid global health cutsMacArthur Foundation awards $100M to outbreak surveillance network, a boost amid global health cutsThe MacArthur Foundation is awarding $100 million to a private pandemic prevention network across Africa, offering critical support to infectious disease surveillance at a time when governments are deprioritizing global health spending.
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