Scientists found memory’s molecular machinery at work in cells outside the nervous system.
Neurons have historically been the cell most associated with memory. But far outside the brain, kidney cells“We’re not saying that this kind of memory helps you learn trigonometry or remember how to ride a bike or stores your childhood memories,” says Nikolay Kukushkin, a neuroscientist at New York University. “This research adds to the idea of memory; it doesn’t challenge the existing conceptions of memory in the brain.
In neurons, when a chemical signal passes through, the cell starts producing CREB. The protein then turns on more genes that further change the cell, kick-starting the). Kukushkin and colleagues set out to determine whether CREB in nonneuronal cells responds to incoming signals the same way. Different timing patterns of pulses resulted in different responses. When the researchers applied four, three-minute chemical pulses separated by 10 minutes, the light 24 hours later was stronger than in cells where the researchers applied a “massed” pulse, a single 12-minute pulse.
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