Key Matchups to Watch as Seattle Seahawks Face San Francisco 49ers in Week 6

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Key Matchups to Watch as Seattle Seahawks Face San Francisco 49ers in Week 6
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Aside from the obvious providing extra support for blocking Nick Bosa, the Seahawks will have to contain Jordan Mason on defense after back-to-back losses.

Rivalry games always raise the stakes in the NFL, but for the Seattle Seahawks and San Francisco 49ers,between NFC West foes carries more significance than usual despite the season still being relatively young in mid-October.

With Lucas still on the PUP list, Forsythe will be tasked with trying to deal with Bosa, which doesn't bode well for the Seahawks based on past precedent. The fourth-year tackle started the first game between these rivals last year in Santa Clara and gave up five pressures and two sacks, struggling to protect Geno Smith while seeing extensive reps against the superstar pass rusher.

Considering Seattle's talented receiving corps, the pressure will fall on Brown and Mustapha to handle one-on-one coverage against Fant and Barner, who have combined to catch 20 passes for 188 yards and a touchdown so far. Though they haven't been a big part of Ryan Grubb's passing game to this point, the two players have been more productive in recent weeks, suggesting that the new play caller has started to figure out how to implement them as complementary targets.

: After only giving his running backs the ball a grand total of seven times on Sunday, Grubb accepted the blame for not running the ball more often against the Giants, and he can't afford to dial up that one-dimensional of an offensive game plan against the 49ers. Walker hasn't had much luck against San Francisco in the past, failing to run for more than 47 yards in any of his three previous regular season matchups against them.

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