Joy True Story: How The Development Of The First IVF Baby, Louise Joy Brown, Really Happened In The '60s & '70s

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Joy True Story: How The Development Of The First IVF Baby, Louise Joy Brown, Really Happened In The '60s & '70s
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Antonella Gugliersi (she/them) is a feature writer for Screen Rant. While studying for her bachelor’s in a completely unrelated subject, they started writing about movies and TV shows for an Italian online publication.

Netflix’s Joy retells the events that led to the development of the first IVF baby, painting a challenging picture because of the obstacles encountered during the scientific process but also the objection of society at large. Releasing on Netflix on November 22, 2024, after a limited run in select cinemas, the biographical drama stars Bill Nighy as gynecologist Patrick Steptoe, James Norton as physiologist Robert “Bob” Edwards, and Thomasin McKenzie as Jean Purdy, the world’s first embryologist.

&#x2715 Remove Ads Bob Edwards Made His First Major Discovery In IVF Potential In 1965 It Happened Before The Involvement Of Jean Purdy & Patrick Steptoe Before directly working with human eggs, Bob Edwards worked with mice, rats and hamster eggs in the early 1960s. Adding hormones to mouse eggs showed the ripening happening simultaneously in mice and in vitro, following the same schedule.

Bob Edwards & Barry Bavister Successfully Fertilized Human Eggs Outside The Womb In 1969 It Was The First Step Toward IVF In Humans &#x2715 Remove Ads Just like Joy showed, once Steptoe became involved, the bulk of the work happened in Oldham. However, the next major step was actually taken in Cambridge by one of Edwards’ PhD students, Barry Bavister.

Jean Purdy & Bob Edwards Devised New Tools & Methods For Embryo Development Throughout The Early 1970s Various Culture Fluids Were Considered & Tools To Collect Eggs Invented The fact that the fertilization was successful but from eggs ripened in vitro meant embryonic development problems would be expected.

&#x2715 Remove Ads Edwards & Purdy's Early IVF Patients Didn't Have A Successful Pregnancy Until 1977 Some Pregnancies Were Ectopic & Others Didn’t Start At All Close Taking human eggs from patients to replant them necessarily involved their expectations, thus causing a high degree of disappointment, as highlighted by Edwards in A Matter of Life and shown in Joy.

1 &#x2715 Remove Ads Between the hormones not consistently helping the pregnancy after the fertilized embryo was replanted and Edwards discovering how the liquid paraffin they used in the process had become toxic, Purdy, Edwards and Steptoe faced obstacle after obstacle. In the end, deciding to follow the menstrual cycle and measuring the surge of the LH hormone to understand when the egg had ripened delivered them success.

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