Scientists have discovered a fluorescent protein that flouts trade-off relationships.
on August 17, the results show that the protein maintaining its brightness even when irradiated by high light has significant implications for fluorescence imaging of biological material.
To avoid interfering with normal biological functions, researchers want to utilize as little fluorescent protein as possible, yet doing so requires employing powerful light in order to get high-quality images. Named StayGold, the fluorescent protein is derived from a naturally occurring fluorescent protein found in"We noticed that the fluorescent protein from the jellyfish was photostable but very dim. And I wasn’t optimistic about making the protein brighter while keeping that photostability because I simply believed the tradeoff,” said Miyawaki“However, to our surprise, we were able to increase both the protein’s photostability and its brightness. So we could have our cake and eat it too.
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