Get the best Jaguars vs. 49ers predictions ahead of Sunday's clash at Levi's Stadium. Free NFL picks for September 28.
The Jacksonville Jaguars hope to pick up a huge road win as they travel to face the unbeaten San Francisco 49ers in a Sunday afternoon battle. The 49ers will welcome Brock Purdy back to the field and hope that the defense can overcome the loss of Nick Bosa.
The Jaguars will need to continue playing well on defense while the offense looks to stop committing so many back-breaking penalties.have a problem on offense, and that is consistently being inconsistent. They rank eighth in the league in total offense, but have a negative EPA/play. They also rank sixth in yards per rush, yet have thrown the ball the sixth-most times of any team. Penalties are a big part of that problem. The Jaguars are racking up more than 72 penalty yards per game, the sixth-most in the NFL, while ranking in the Top 10 of most penalties per play. performance, as the Jags have the second-worst passing completion rate in the NFL. And this is despite his offensive line allowing the second-fewest pressures in the league. The good news for the Jaguars is how well the defense is playing. They’ve notched nine takeaways through three games, are holding opponents to the fourth-fewest yards per pass attempt, and are limiting teams to below 210 passing yards per game despite facing the second-highest passing rate.will present a tougher challenge than what Bryce Young and CJ Stroud could. But he’s banged up, will be without George Kittle, and he’s going to face a system that is limiting big plays. He’s also playing behind a line that has allowed 10+ pressures in all three games. still looking to get going. He’s averaging just 3.4 yards per carry this season, and hasn’t topped 70 yards in a game despite already getting 52 carries. That includes just 55 yards on 13 carries against New Orleans. The loss of Nick Bosa is a blow, but I’m not sure the 49ers will need it. Jacksonville will continue shooting itself in the foot on offense and falling behind the chains, while the 49ers will continue their struggles to score touchdowns in the red zone. While McCaffrey’s rushing numbers haven’t been good, he’s doing damage in the passing game. He’s already caught 25 passes through three games, with 52+ receiving yards in all three games. Jacksonville ranks in the Top 10 in QB pressures, and Purdy’s going to look for his safety valve early and often. Toss in the designed pass plays to get CMC involved, and he’ll top that total fairly easily.has had a solid start to the season, he’s also benefited from his offensive line giving him the second-most yards before contact of any back in the league.has seen an uptick in carries the last two weeks and has already done a good job of forcing missed tackles. I expect he’ll see a higher share of the carries against the solid San Francisco front seven and get to at least 25 yards on the ground. Jacksonville has the second-best tackle rate of any defense in the NFL and has allowed the fewest yards after contact of any team. Given McCaffrey’s struggles to run the ball, it’s hard to see him suddenly breaking out against the Jags. On the flip side, he’s already been targeted 31 times this season. That’s more than any other back in the league, and he’s coming off a game where he caught 10 passes for 88 yards against the Cardinals. With Kittle still sidelined, expect him to keep getting a high volume of passes thrown his way. The San Francisco 49ers have covered the 1Q Spread in 15 of their last 20 games . Find more: Our team of experts has thoroughly researched and handpicked each product that appears on our website. We may receive compensation if you sign up through our links. Jason has been hooked on football since watching Real Madrid and Manchester United in the 2003 Champions League, and has been betting on the sport for nearly 15 years. He has given soccer gambling and fantasy advice for nearly a decade, writing for sites including Rotowire, SB Nation, and The TwinSpires Edge.Copyright © 1995 - 2025 CS Media Limited All Rights Reserved. If you choose to make use of any information on this website including online sports betting services from any websites that may be featured on this website, we strongly recommend that you carefully check your local laws before doing so.It is your sole responsibility to understand your local laws and observe them strictly.Covers does not provide any advice or guidance as to the legality of online sports betting or other online gambling activities within your jurisdiction and you are responsible for complying with laws that are applicable to you in your relevant locality.Covers disclaims all liability associated with your use of this website and use of any information contained on it.As a condition of using this website, you agree to hold the owner of this website harmless from any claims arising from your use of any services on any third party website that may be featured by Covers.
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