Jacksonville could be first in nation to launch gene editing study for cholesterol

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Jacksonville could be first in nation to launch gene editing study for cholesterol
HealthResearchGene Editing
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A local research group is preparing to launch a first-of-its-kind gene editing study aimed at helping people with severe cholesterol conditions, and it could permanently change how the disease is treated.

President Donald Trump talks with Gov. Ron DeSantis, R-Fla., during a roundtable at"Alligator Alcatraz," a new migrant detention facility at Dade-Collier Training and Transition facility, Tuesday, July 1, 2025, in Ochopee, Fla.

Isolated storms possible as temperatures climb into the 80s this weekPolice seize 9 guns, over 100 grams of marijuana, make 13 arrests after learning of ‘Senior Skip Day’ event at Jax Beach Read full article: Police seize 9 guns, over 100 grams of marijuana, make 13 arrests after learning of ‘Senior Skip Day’ event at Jax BeachA local research group is preparing to launch a first-of-its-kind gene editing study aimed at helping people with severe cholesterol conditions, and it could permanently change how the disease is treated.Gene editing refers to a group of technologies that allow scientists to precisely add, remove, or alter DNA within an organism’s genome. Researchers are now applying that technology to tackle serious cholesterol problems through the liver. Dr. Michael Koren, with Encore Research Group of Jacksonville Center for Clinical Research, is set to lead the study. “We could be the first place in the United States, in all of the U.S., to do gene editing studies for cholesterol issues,” Koren said.One such condition is familial hypercholesterolemia, a genetic disorder that causes dangerously high cholesterol levels from birth. “There is a genetic type of cholesterol problem called familial hypercholesterolemia that affects between 1 in 300 and 1 in 500 people in the U.S.,” Koren said. People diagnosed with the disorder often face serious health consequences early in life, including the potential need for surgery or a heart attack before age 65. While medications can help manage cholesterol levels, this study marks the first time a therapy has aimed to reverse the underlying problem rather than simply treat its symptoms. The new therapy would permanently lower cholesterol levels, potentially reducing the risk of heart attacks and other dangerous health complications.The Jags are about to get a new 'home away from home' for 2027Lawmakers hope new law spurs affordable housing, but some say it weakens local government controlWoman found fatally shot in front yard of home on Jacksonville’s WestsideFlorida court shuts down online gift card business based in Ponte Vedra, imposes over $800K in finesDNA test connects Clay County Navy veteran to WWII POW missing for over 80 yearsSt. Augustine replacing downtown parking kiosks with cashless touchscreensHundreds participate in Jacksonville ‘No Kings’ rally against Trump administrationFlagler College students protest housing policy as seniors cite affordability, availability concernsGAME DAY ⚾🦐 The defending Triple-A National Champion Jacksonville Jumbo Shrimp returnShould an HOA or property management company be required to post parking rules for visitors?Fights erupt at Palatka Junior-Senior High after field trip focused on mental healthMother of teen punched during arrest says officer went too far

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