Is cannabidiol effective against COVID-19? Coronavirus Disease COVID Antibodies AntiInflammatory Asthma Cannabidiol Cannabinoid Cannabis LiebertPub LMU_Muenchen
By Dr. Liji Thomas, MDJul 31 2022Reviewed by Benedette Cuffari, M.Sc. The coronavirus disease 2019 , which is caused by infection with the severe acute respiratory syndrome coronavirus 2 , has caused over 6.4 million deaths to date.
A wide range of drugs has been evaluated for their ability to mitigate COVID-19 severity. These includes dexamethasone, a powerful corticosteroid with anti-inflammatory and immunosuppressive activity; remdesivir, a nucleoside analog that inhibits viral replication; hydrochloroquine, an immunomodulatory antimalarial drug, convalescent plasma containing specific antibodies to the virus, as well as SARS-CoV-2 monoclonal antibodies.
Paxlovid and molnupiravir have been given emergency use authorization for the treatment of high-risk COVID-19-positive patients. These agents are suitable only for those with early symptoms who are not receiving any other treatment for severe COVID-19. Related StoriesSide effects of CBD include sleepiness, fever, poor appetite, abnormal behavior, and euphoria. Further research is needed to determine the relevance of these side effects following chronic use.
In the in vitro human tissue models, CBD treatment was associated with a lower expression of A2A receptors and reduced inflammation. As compared to dexamethasone, CBD reduced inflammatory signaling induced by lipopolysaccharide, which is a potent bacterial inflammation-inducing antigen
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