Omitting axillary surgery in patients with early breast cancer who had sentinel-node metastases and underwent surgery and radiotherapy did not compromise survival outcomes, new data show.
Omitting axillary lymph node dissection does not increase the risk for recurrence or compromise 5-year overall survival outcomes in patients with early-stage, node-negativeA growing body of evidence has indicated that patients with one or two positive sentinel nodes undergoing breast-conserving surgery and radiation therapy can skip axillary lymph node dissection and achieve similar outcomes compared with patients...
To fill the gaps in the literature, the researchers conducted a trial with a large, inclusive cohort of patients with node-negative stage T1-T3 breast cancer who had one or two sentinel-node macrometastases and had undergone a Earlier recurrence-free survival findings and patient-reported outcomes were reported last December. The researchers now reported overall survival findings as well as secondary endpoints of breast cancer-specific survival.The researchers reported 191 recurrences or deaths over a median follow-up of 46.8 months; 62 patients in the sentinel-node biopsy–only group died, and 69 patients in the dissection group died.
Malignant Breast Neoplasm Breast Carcinoma Breast Mammary Gland Breast Conserving Surgery Conservative Breast Surgery Breast Preservation Surgery Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Metastasis Metastatic Carcinoma Metastatic Cancer Metastases Genomics Genomic Medicine Surgery Radiation Therapy Radiotherapy Radiation Oncology Lymph Node Dissection
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