Switching to a different class of biologic improves psoriasis outcomes but may raise infection risk in some cases, a meta-analysis suggests.
Interclass biologic switching is effective and safe in patients with psoriasis, though switching from an anti-tumor necrosis factor -alpha to an anti-interleukin -17A treatment was associated with higher risk for adverse events , according to a meta-analysis.
No major safety differences were observed overall, except for increased serious adverse events when switching from an anti-TNF-alpha agent to an anti-IL-17A agent .
Biologic Therapy Biologics Anti-TNF Anti-Tumor Necrosis Factor Anti-Tumour Necrosis Factor Anti-Tumor Necrosis Factor (Anti-TNF) Meta-Analysis Medical Innovations Innovations In Medicine Innovation Hospitals Clinical Research Clinical Trials Clinical Studies Pre-Clinical Trial Double-Blind Study Double-Blind Studies Single-Blind Study Single-Blind Studies
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