After 20 weeks of a multimodal lifestyle intervention, patients with MCI or early AD experienced improved cognition, results of a phase 2 trial suggested.
Healthy behaviors have been linked to a lower risk for Alzheimer's disease but may also benefit patients already diagnosed with mild cognitive impairment or early AD, new research suggested.
Beneficial changes were also observed in several biomarkers, including plasma amyloid beta 42/40 ratios, which increased by 6.4% in the intervention group and dropped by 8.3% in the control group scores improved in the intervention group from 0.69 to 0.65 and worsened in the control group from 0.66 to 0.74 scores improved from 21.55 to 20.53 in the intervention group and worsened in the control group from 21.25 to 22.
"One patient said it used to take weeks to finish a book, but after being in the study, he was able to do so in just 3 or 4 days and remember most of what he read," said Ornish."One guy wasn't able to play the bagpipes because he couldn't remember the notes, and now he can, and he's actually teaching a student to do so.", Heather M.
"For now, there is an opportunity for providers to incorporate or expand messaging with their patients and families about the habits that they can incorporate into their daily lives," Snyder said. The Alzheimer's Association offersOf note, the current study showed that higher adherence to the multimodal lifestyle intervention was required to improve cognition and function in participants. In the primary analysis, this ranged from 71.4% adherence for ADAS-Cog, 95.
Alzheimer Disease Mild Cognitive Impairment MCI - Mild Cognitive Impairment Minimal Cognitive Impairment MCI Mild Cognitive Impairment (MCI) Cognition Dementia Exercise Physical Activity Complementary And Alternative Medicine Alternative Treatment Alternative Medicine Complementary Medicine Alternate Medical Therapy Alternate Medicine Lipids Lipid Management
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