For patients with diabetes, a systolic target of 120 mm Hg led to a significant reduction in CV events in BPROADS, mirroring results from SPRINT in patients without diabetes.
CHICAGO — An intensive treatment approach to lower systolic blood pressure to a target of 120 mm Hg in patients withIn the new Chinese clinical trial, the relative risk of a major cardiovascular event was 21% lower with intensive treatment than with standard treatment during the 4-year follow-up period.
In addition, the ESPRIT trial"recently showed a 12% lower risk of major vascular events among patients with and those without diabetes" who received intensive blood pressure lowering treatment, they add. Patients were randomized to receive intensive treatment, with a systolic blood pressure target of less than 120 mm Hg, or standard treatment, with a target of less than 140 mm Hg, for up to 5 years.
The study confirms that people with diabetes have the same response as those without diabetes in terms of benefit from more aggressive blood pressure lowering, added Shawna Nesbitt, MD, which had been uncertain because of the unclear results of the ACCORD trial. In clinical practice, however,"while we are very happy to see that intensive reduction of blood pressure reduces events, we do have to be concerned about the serious adverse events that these changes in blood pressure may cause, particularly in elderly people," she said.
The BPROAD trial confirms that patients with diabetes should have the same blood pressure targets as patients without diabetes, Jane Leopold, MD, director of the Women's Interventional Cardiology Health Initiative at Brigham and Women's Hospital in Boston, Massachusetts, and deputy editor of the
Blood CV Risk Cardiovascular Risk CV Risk Factors Cardiovascular Risk Factors Cardiovascular Risk Management Diabetes Mellitus Type 2 Diabetes Mellitus Type Ii Type 2 Diabetes Type 2 DM T2DM T2D Cardiac Surgeries Cardiac Surgery Heart Failure Stroke Cerebrovascular Accident CVA - Cerebrovascular Accident Patient Safety Myocardial Infarction Cardiovascular Disease
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