In a health breakthrough, scientists at the UC Davis Comprehensive Cancer Center in Sacramento, California, have identified a protein on the CD95 receptor that can “program' cancer dells to die.
Researchers say they've located a 'kill switch' that can trigger the death of cancer cells. Scientists at the UC Davis Comprehensive Cancer Center in Sacramento, California, have identified a protein on the CD95 receptor that can 'program' cancer cells to die, as detailed in a study published in the journal Cell Death & Differentiation last month. A receptor is a protein within a cell that receives and transmits signals.
receptors — also referred to as Fas — have gained the nickname 'death receptors' because they send a signal that causes cancer cells to 'self-destruct,' according to a press release from UC Davis. 'Previous efforts to target this receptor have been unsuccessful.
It is evident that the success of CAR-T therapy relies on off-target killing by Fas,' he told Fox News Digital. 'With the current information, we researchers and doctors should screen potential cancer patients — who would be undergoing CAR-T therapy — to check for the comprehensive presence of Fas on their tumors,' he went on.
Due to the advent of cancer immunotherapy and other targeted therapies, cancer rates overall in the past decades have decreased significantly,' he said. 'I read every day the outstanding research that is happening in the U.S. to beat cancer. People should stay positive.' Added Tushir-Singh, 'The next breakthrough is just one experiment away.' For more Health articles, visit www.foxnews.com/health.
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