Immunotherapy to treat cancer gave rise to 2nd cancer in extremely rare case

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Immunotherapy to treat cancer gave rise to 2nd cancer in extremely rare case
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Miriam Bergeret is a science writer and editor based in Toronto, Canada. Miriam holds a master's degree in laboratory medicine and pathobiology from the University of Toronto, where she also studied science journalism and communication.

In an extremely rare case, a patient who received a cell-based cancer treatment later developed a second cancer that arose from the treatment itself.

Despite the low risk, these sporadic cases have drawn scrutiny from the FDA and left the research community with unanswered questions about the underlying causes and potential risk of CAR-related secondary cancers. The FDA maintains that the overall benefit of these therapies outweighs potential risks, but the agency wants to better understand the risks, nonetheless.

By submitting your information you agree to the Terms & Conditions and Privacy Policy and are aged 16 or over.The tumor was CAR-positive, indicating that the cancer had arisen from one of the immune cells modified for the woman's treatment.

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