Researchers have shown that sleep enhances the migratory potential of T cells toward lymph nodes.
Researchers at LMU Munich have shown that sleep enhances the migratory potential of T cells toward lymph nodes.
Analysis of the blood samples revealed significant differences between the test conditions:"Our results show that sleep promotes the migratory potential of various T-cell subpopulations," says Besedovsky.As the researchers demonstrated, sleep increases the directed migration of T cells toward a signaling protein, the so-called 'homing' chemokine CCL19.
"Our results also have potential clinical implications," says Besedovsky."Thus, growth hormone and prolactin could be considered as new adjuvants to promote immune responses following vaccination, especially in aged people, who typically display reduced levels of these hormones during sleep.
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