When weighing dietary interventions, clinicians should consider symptom improvements alongside diet complexity, cost, and potential micronutrient deficiencies.
, combining a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols and a gluten-free diet appears to improve clinical symptoms and reduce anxiety andAcross several studies, the combined diet improved quality of life and reduced bloating, stomach pain, and the severity of IBS symptoms, lead author Jing Zhang of the Yangzhou University School of Nursing in Jiangsu, China, and colleagues found.
However, the “small and inconclusive” nature of existing research prompted their review of the efficacy of a low-FODMAP combined with a gluten-free diet in adult patients with IBS, the authors wrote.Zhang and colleagues analyzed data for 437 patients with IBS across four randomized controlled trials and four cohort studies.
Patients in the LF-GFD group also had reductions in self-reported depression scores and self-reported anxiety scores compared to the GFD group. In this study, Chey noted, the randomized controlled trials all carried at least a moderate risk of bias, and the cohort studies would be considered of low methodologic quality. In addition, an LF-GFD was compared to a GFD rather than a low-FODMAP diet, which could have been a more compelling comparison for IBS treatment, he said.
Irritable Bowel Syndrome (IBS) IBS Diet Bloating Abdominal Bloating Anxiety Pain Quality Of Life QOL Health Related Quality Of Life Health-Related Quality Of Life HRQOL Anxiety Disorder Depression Pain Management Healthcare And Medical Technology Health And Medical Tech Health And Med Tech Health And Medical Technology Healthcare Technology
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