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Getting older might seem like a slow, gradual process – but research suggests that this is not always the case. In fact, if you wake up one morning, look in the mirror, and wonder if your aging somehow accelerated, you might not be imagining things.
, humans experience two abrupt lurches forward, one at the average age of 44 and the other at around age 60."It turns out the mid-40s is a time of dramatic change, as is the early 60s. And that's true no matter what class of molecules you look at."Using the samples from their cohort, the researchers tracked various kinds of biomolecules. The different molecules studied include RNA, proteins, lipids, and microbiome taxa from the gut, skin, nasal, and oral regions, for a total of 135,239 biological features. Each participant submitted an average of 47 samples over 626 days, with the longest-serving participant providing 367 samples. This wealth of data resulted in more than 246 billion data points, which the researchers then processed, looking for patterns in the changes. Snyder and his colleagues observed a distinct change in the abundance of many different kinds of molecules in the human body at two distinct stages. Around 81 percent of all the molecules they studied showed changes during one or both of these stages. Changes peaked in the mid-40s, and again in the early 60s, with slightly different profiles., but the researchers ruled this out as a main factor: Men, too, also underwent significant molecular changes at the same age. "This suggests that while menopause or perimenopause may contribute to the changes observed in women in their mid-40s, there are likely other, more significant factors influencing these changes in both men and women,"47-Year Study Reveals The Age We Hit Our Physical Peak The researchers note that their sample size is pretty small, and they tested limited biological samples, from people between the ages of 25 and 70. Future research could dive further into this phenomenon, studying it in more granular detail, across a wider range of subjects, to better understandBig breakthroughs. Bold ideas. Straight to your inbox.
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