How Psychological Distress Affects GI Symptom Severity in Ulcerative Colitis

Psychological distress predicts symptom severity and mental health-related quality of life in patients newly diagnosed with ulcerative colitis.

Baseline psychological distress predicts gastrointestinal symptom severity and mental health-related quality of life over time in patients newly diagnosed withThere is limited knowledge about the longitudinal evolution of UC symptoms, the underlying biopsychosocial processes, and the dynamic relationship between symptoms, psychological distress, and systemic inflammation over time.

Researchers assessed 98 adult patients with new-onset UC from two outpatient gastroenterology clinics in Sweden. Biopsies, blood samples, and fecal samples were collected from the patients at diagnosis, and various self-report questionnaires were administered at study inclusion and over 3 years to assess severity of gastrointestinal symptoms , while diarrhea and abdominal pain negatively predicted changes in coping resources over time.

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Medscape /  🏆 386. in US

Ulcerative Colitis (UC) UC - Ulcerative Colitis Abdominal Pain Pain Management Inflammatory Bowel Disease IBD - Inflammatory Bowel Disease IBD Diarrhea Diarrhoea Colitis Quality Of Life QOL Health Related Quality Of Life Health-Related Quality Of Life HRQOL Abdominal Pain Depression Biologic Therapy Biologics Anxiety Anxiety Disorder Biopsy Blood Crohn's Disease

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