How fentanyl kills—and how Narcan saves lives

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How fentanyl kills—and how Narcan saves lives
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The steady increase in opioid overdose deaths across the U.S.—which more than doubled among teens in just two years—has heightened debate over the role of naloxone in the front lines of American addiction

, has sharply reduced heroin supply. With less heroin available, demand for fentanyl—a cheap, potent replacement for other opioids—has risen.

Then, “there’s an enormous market of counterfeit pills,” Hadland says. A crackdown on opioid prescribing made it harder to get real prescription pills just as fentanyl became easy to produce and import into the U.S. Often when teens think they’re buying oxycodone, Xanax or even Adderall, they’re buying a fake pill made with fentanyl. Young people are less likely to have built up a tolerance through prior opioid use, so they’re particularly at-risk for overdosing.

The final issue is contamination when dealers prepare or manufacture drugs on the same surfaces used for fentanyl. Tiny amounts of fentanyl contamination can lead to an overdose, especially in people intending to use cocaine, MDMA or methamphetamine who haven’t built up a tolerance.

Key to reducing opioid overdose deaths, then, is ensuring wide accessibility to naloxone, particularly for those who use drugs and their friends and family. If students have to ask the school nurse for naloxone, it’s less useful than if it were available for free in vending machines, as

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