Scientists' discovery could lead to new weight loss and metabolic health treatments.
Neuroscientists at Scripps Research have identified brain circuits that make mammals want to eat more when they are exposed to cold temperatures.
One of their first observations was that, with the onset of cold temperatures , mice increase their food seeking only after a delay of about six hours, suggesting this behavioral change is not simply a direct result of cold sensing. In a last set of experiments, the team showed that these xiphoid nucleus neurons project to a brain region called the nucleus accumbens -- an area long known for its role in integrating reward and aversion signals to guide behavior, including feeding behavior.
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