Household transmission of endemic human coronaviruses in the US CUDenver JohnsHopkinsSPH Cambridge_Uni human coronavirus humancoronavirus transmission humantransmission household householdtransmission
By Neha MathurMay 9 2023Reviewed by Lily Ramsey, LLM In a recent study published in the Journal of Infectious Diseases, researchers performed a large household transmission study to describe clinical outcomes of endemic human coronavirus infections and the risk of household and community-level transmission likelihoods in Allegheny County, Pennsylvania, in the United States Of America .
Endemic hCoVs cause respiratory illnesses, on average, at least once in children below five years. All four hCoV strains, HCoV-229E, HCoV-HKU1, HCoV-OC43, and HCoV-NL63, will have infected people by adulthood. Serology and virological studies have shown that they reinfect people throughout their lives.
Related StoriesThe study population experienced 121 RT-PCR-confirmed seasonal hCoV infections, assessed by weekly disease surveillance over two respiratory virus seasons, December 2015–April 2016 and January 2017–May 2017. The study focused primarily on four hCoVs, viz., HCoV-229E, HcoV-HKU1, HcoV-NL63, and HcoV-OC43, and five age groups, children less than five years, children between five to nine years, adolescents aged 10 to 19 years, adults aged 20 to 49 years, and ≥50-year adults.
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