This project will be mainly supported by a newly funded NIH R01 with Dr. Matthew Greenblatt of Weill Cornell Medicine and Dr. Xu Yang of the Arthroplasty Research Lab at the Hospital for Special Surgery as Co-PIs.
We will develop key initial elements of a new approach for the regeneration of amputated limbs, by transducing a specific population of autologous skeletal stem cells to induce a blastema-like state, and then implanting them into the amputation site to initiate regeneration of the missing limb.
A candidate having a recent Ph.D. degree in Developmental Biology, Cell and Molecular Biology, or Neuroscience will be desirable. Writing skill and expertise in mouse genetics, light and confocal microscopy, and gold-stand techniques of cell and molecular biology are required. The candidate is expected to have one or more high quality first author publications on cell biology or mouse models of disease or both.
Standardize and establish new published procedures; evaluate innovative techniques. Develop new assays and new protocols for research. Maintain optimal protocol and assay accuracy by conducting regular quality and reproducibility checks. Timely compile, present and discuss relevant insights about experimental results with Principal Investigator.
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