Nature research paper: Hippocampal astrocytes encode reward location
Extended Data Fig. 3 Astrocytic Activity Does Not Ramp Towards Rewarding Location in a New Environment. The correlation between location and astrocytic activity in repeated active ROIs was significantly higher in the familiar environment compared to the new one .
Extended Data Fig. 3 Astrocytic Activity Does Not Ramp Towards Rewarding Location in a New Environment.. The correlation between location and astrocytic activity in repeated active ROIs was significantly higher in the familiar environment compared to the new one . The repeated active ROI pairs that had significant mutual information in each environment of the mouse shown in Fig.. The mean proportion of significant MI repeated active ROI pairs in the familiar environment is significantly higher than in the new environment . The mean normalized number of concurrent events as a function of location in the familiar environment and in the new environment for all active ROIs, not just the repeated ones, in the 7 mice shown in Fig.. The ramping of astrocytic activity is significantly larger in the familiar environment than in the new environment . Two mice were imaged for the third time in the familiar environment after the exposure to the new environment. The mean normalized number of concurrent events as a function of location shows that ramping is maintained . Data presented as mean ±SEM . Different mice are colour-coded as in Fig.
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