Today's higher-potency cannabis products put teens at risk for impaired brain development; mental health issues, including psychosis; and CUD.
It's becoming clear that adolescent brain is particularly vulnerable to cannabis, especially today's higher-potency products, which put teens at risk for impaired brain development; mental health issues, including psychosis; and cannabis use disorder .
Tetrahydrocannabinol concentrations in cannabis products have increased over the years, from around 2%-4% to 15%-24% now, Hurd noted. Cannabis exposure during neurodevelopment has the potential to alter the endocannabinoid system, which in turn, can affect the development of neural pathways that mediate reward; emotional regulation; and multiple cognitive domains including executive functioning and decision-making, learning, abstraction, and attention – all processes central to substance use disorder and other psychiatric disorders, Hurd told the briefing.
The first is age, both for the onset and frequency of use at younger age. Those who start using cannabis before age 16 years are at the highest risk for CUD. The risk for CUD also increases significantly among youth who use cannabis at least weekly, with the highest prevalence among youth who use cannabis daily. One large study linked increased frequency of use with up to a 17-fold increased risk for CUD.
Another challenge is that treatment strategies for CUD are currently limited and consist mainly of motivational enhancement and cognitive-behavioral therapies. Yet, on a positive note, the"plasticity of the developing brain that makes it vulnerable to cannabis use disorder and psychiatric comorbidities also provides an opportunity for prevention and early intervention to change that trajectory," Hurd said.
Adolescent Medicine Teens Teenage Teenager Adolescent Health Adolescents Adolescent Brain Psychosis Drug Abuse Abuse Cannabis Compound Abuse Cannabinoid Marijuana Mental Illness Mental Disorder Psychiatric Disorder Psychiatric Illness Schizophrenia Cognitive-Behavior Therapy CBT Cognitive Behavioral Therapy Endocannabinoids New York Oregon Young Adult
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