Here's exactly how thin the iPhone 15 Pro bezels are likely to look

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Here's exactly how thin the iPhone 15 Pro bezels are likely to look
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Slimming down

has also put together some renders showing the front of the iPhone, based on previous rumors from Mark Gurman and others – so you've got a choice of unofficial pictures to refer to.

tapping up its suppliers for bezel-less iPhone OLED panels, but they're not going to be ready for September 2023 and the iPhone 15.Sign up to receive daily breaking news, reviews, opinion, analysis, deals and more from the world of tech.Receive email from us on behalf of our trusted partners or sponsors

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Inflammatory cytokines as potential biomarkers for early diagnosis of severe malaria in children in Ghana - Malaria JournalInflammatory cytokines as potential biomarkers for early diagnosis of severe malaria in children in Ghana - Malaria JournalBackground Severe malaria (SM) is a fatal multi-system disease which accounted for an estimated 619,000 deaths in 2021. Less than 30% of children presenting with SM are diagnosed and treated promptly, resulting in increased mortality and neurologic impairments in survivors. Studies have identified cytokine profiles that differentiate the various clinical manifestations of malaria (severe and uncomplicated). However, the diagnostic capability of these cytokines in differentiating between the disease states in terms of cut-off values has not yet been determined. Methods The plasma levels of 22 pro-inflammatory cytokines (Eotaxin/CCL 11, interferon-gamma (IFN-γ), interleukin (IL)- 2, IL-6, IL-1β, IL-12p40/p70, IL-17A, RANTES, MCP-1, IL-15, IL-5, IL-1RA, IL-2R, IFN-α, IP-10, TNF, MIG, MIP-1α, MIP-1β, IL-7, IL-8 and Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF), and 3 anti-inflammatory cytokines-(IL-4, IL-13 and IL-10) in patients with SM, uncomplicated malaria (UM) and other febrile conditions, were measured and compared using the Human Cytokine Magnetic 25-Plex Panel. The receiver operating characteristic (ROC) curve analysis was used to determine the diagnostic value of these cytokines. Results The level of the pro-inflammatory cytokine, IL-17A, was significantly higher in the SM group as compared to the UM group. Levels of the anti-inflammatory cytokines however did not differ significantly among the SM and UM groups. Only IL-1β and IL-17A showed good diagnostic potential after ROC curve analysis. Conclusion The data show that levels of pro-inflammatory cytokines correlate with malaria disease severity. IL-1β and IL-17A showed good diagnostic potentials and can be considered for use in clinical practice to target treatment.
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