'Until recently, the best we could do was slow aging. New discoveries suggest we can now reverse it.' Find out more at 🚀 engineering interestingengineering
The researchers screened for molecules that could reverse cellular aging and rejuvenate human cells. They first distinguished young cells from old cells and identified “six chemical cocktails that restore NCC and genome-wide transcript profiles to youthful states and reverse transcriptomic age in less than a week.”
“Studies on the optic nerve, brain tissue, kidney, and muscle have shown promising results, with improved vision and extended lifespan observed in mice and, recently, a report of improved vision in monkeys,” noted Sinclair in a tweet.that even though the 'cocktail' may have useful therapeutic properties, there is no direct data in Sinclair's paper that ties evidence to his claims.
"They should have validated at least one of these cocktails in an animal and shown improvements in age-related health metrics or lifespan before making these claims about effects on biological aging," added Kaeberlein. Another researcher, Dr Charles Brenner, said that the cocktail contained compounds that can put people at risk and are 'generally not safe alone or in a combination'.
While Sinclair has hailed his research as 'a breakthrough discovery', it remains to be seen if his claim will be a hard pill to swallow by the scientific community at large.A hallmark of eukaryotic aging is a loss of epigenetic information, a process that can be reversed.
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