Grapefruit Can Mess With Your Meds, But Scientists May Have a Solution

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Grapefruit Can Mess With Your Meds, But Scientists May Have a Solution
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inside grapefruit that interfere with prescription drugs , which is why people on these meds are often advised to cut out certain fruits from their diet.A team from The Volcani Center in Israel decided to look for the genes behind furanocoumarins in the citrus fruits, grapefruit and. They were able to find a multi-gene cluster in the 2-oxoglutarate-dependent dioxygenase family that was responsible for producing the defensive plant compounds.

"This research helps us to understand why fruit of certain citrus species produce furanocoumarins and demonstrates how breeders and researchers could develop furanocoumarin-free citrus varieties,"Different genes in the 2OGD cluster were shown to be responsible for its production in different parts of the plant , or under different conditions . The integrity of one gene in particular, Cg2g000710, seems to be crucial in cooking up furanocoumarins.

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