Researchers have used a new gold-based drug to slow tumor growth in animals by 82% and target cancers more selectively than standard chemotherapy drugs, according to a new study.
A new gold-based drug can slow tumour growth in animals by 82% and target cancers more selectively than standard chemotherapy drugs, according to a study by Australian and Indian researchers.reveals a new gold-based compound that's 27 times more potent against cervical cancer cells in the lab than standard chemotherapy drug cisplatin.
"These newly synthesized compounds demonstrate remarkable anticancer potential, outperforming current treatments in a number of significant aspects including their selectivity in targeting cancer cells," said Bhargava, Director of RMIT's Centre for Advanced Materials and Industrial Chemistry.Towards more targeted, less toxic treatment
By blocking this protein's activity, the gold compound effectively shuts down cancer cells before they can multiply or develop drug resistance. Project co-lead at RMIT, Distinguished Professor Magdalena Plebanski, said along with this ability to block protein activity, the compound also had another weapon in its anti-cancer arsenal.
This included ovarian cancer cells, which are known to develop resistance to cisplatin treatment in many cases. Meanwhile, RMIT Vice-Chancellor's Research Fellow Dr Ruchika Ojha has been supporting Bhargava in building and leading his Molecular Engineering Group to continue advancing innovative research into gold-based therapeutics long into the future.
Today, gold-based cancer treatments are gaining global traction, with advancements such as the repurposing of the anti-arthritic drug auranofin, now showing promise in clinical trials for oncology.
Cancer Lung Cancer Breast Cancer Prostate Cancer Leukemia Ovarian Cancer Brain Tumor
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