Gilead is launching a phase 1 clinical trial of an inhaled version of remdesivir, a drug used to treat Covid-19, that could be administered to patients outside of the hospital
, it said in a statement released Wednesday.... [+]
drug Remdesivir in particularly severely ill patients at the University Hospital Eppendorf in Hamburg, northern Germany on April 8, 2020, amidst the new coronavirus COVID-19 pandemic. Though there are no drugs approved by the FDA to treat Covid-19, Remdesivir is one of the more promising candidates and was granted anIn the hospital remdesivir is given intravenously, but the new trial will test whether it is effective if breathed directly into the lungs.
The medication would be given to patients through a nebulizer, a device commonly used to treat asthma that turns liquid medication into a breathable mist. If inhaled remdesivir is successful, it could be an at-home or doctor’s office treatment for patients who are not sick enough to need hospitalization, but still could benefit from medication.
The new trial will include approximately 60 adults, and will test first for safety and tolerability of the inhaled medication.“Based on current scientific understanding, the upper respiratory tract is the most prevalent site of SARSCoV-2 infection early in disease,” said Gilead’s Chief Medical Officer Merdad Parsey in a statement.
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