Researchers using modern gene-editing tools have discovered that the intuition of scientists from more than a century ago was right: Cells with unusual numbers of chromosomes are drivers of cancer.
found that the more chromosomally unstable a patient’s tumor cells were, the more likely their cancer was aggressive and their prognosis poor.
With the invention of CRISPR gene editing technology a decade ago, scientists gained the ability to add, delete or tweak genes. But deleting a whole chromosome is a different matter. When they tried to grow tumors from this subpopulation of cancer cells, they found that the cells were no longer capable of seeding tumors in a petri dish or in live mice. To Sheltzer, this was clear evidence that extra chromosomes weren’t just an effect, but a driver of the disease.For now, the technique is a tool, not a therapy. It’s not yet feasible to think about restoring normal numbers of chromosomes in cancer cells as a way of staving off the disease.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Velocity Modern Classics now in the vintage Ford F-100 game - AutoblogVelocity Modern Classics now in the vintage Ford F-100 game, another Signature Series pickup range joining the F-1250, Bronco, and Blazer.
Read more »
Taylor Swift Extends Record Run Atop Artist 100 Chart to 71 Weeks.taylorswift13 spends a record-extending 71st week at No. 1 on the Artist100 chart! 👏
Read more »
A Guide to Black Art in DC: Emerging Artists, Galleries, and MoreA Guide to Black Art in DC: Emerging Artists, Galleries, and More 100 years of innovative and enduring work
Read more »
Restaurateur launches Southtown ghost kitchen in 100 square feetA former brick-and-mortar restaurateur is attempting to launch a ghost kitchen business — in 100 square feet of space in an old convenience store.
Read more »
Hot 100 First-Timers: Jasiel Nunez Debuts With Peso Pluma Collabs ‘Lagunas’ & ‘Rosa Pastel’The songs start at Nos. 90 and 93, respectively.
Read more »
Glendale man fired 100 rounds into air during 'height of 4th of July celebration,' police saySHANNON'S LAW ARREST: A man who police say violated Shannon's Law by firing gunshots into the air during Fourth of July celebrations in Glendale was arrested.
Read more »