Adenoma detection rates were shown to be comparable between 45-49-year-olds and 50-54-year-olds.
, the adenoma detection rate in screening colonoscopies is 28%, which is comparable with rates seen in those aged 50-54 years.The rising incidence of CRC in younger populations prompted most guidelines to recommend screening to start at age 45. The impact of lowering the screening age on adenoma and sessile serrated lesion detection rates remains unclear, however.
The primary outcome was the overall detection rates of adenomas and sessile serrated lesions for colonoscopies performed for any indication.Across 15 studies, 41,709 adenomas were detected in 150,436 colonoscopies performed for any indication, resulting in a pooled overall ADR of 23.1%. Across six studies, 1162 sessile serrated lesions were reported in 11,457 colonoscopies performed for any indication, with a pooled detection rate of 6.3%.
Across seven studies, the pooled ADR in screening colonoscopies performed on individuals with average CRC risk was 28.2%, which is comparable with that of 50- to 54-year-old individuals undergoing screening colonoscopy. There was not enough data to calculate the sessile serrated lesion detection rate in average-risk patients.
Colorectal Cancer (CRC) Bowel Preparation Colonoscopy Meta-Analysis Preventive Screening Screening Minnesota Canada Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Clinical Guidelines Guidelines
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