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A common type of fungi has now been shown to penetrate the mammal brain and trigger toxic amyloid plaques like those associated with
Amyloid protein clumps that show up between neurons are strongly associated with Alzheimer's disease, and are generally thought to be the result of intrinsic stress or inflammation in the brain. To explore that idea further, an international team of researchers, led by experts at Baylor College of Medicine in the United States, has turned to mice.straight into the brains of mice. Four days later, the mice were euthanized and their brains were used for further analysis.can trigger two neuroimmune mechanisms, one which activates immune cells that suppress the fungi, and another that triggers them into removing the intruder altogether.
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Fungal infection in the brain produces changes like those seen in Alzheimer's diseaseResearchers have discovered how the fungus Candida albicans enters the brain, activates two separate mechanisms in brain cells that promote its clearance, and, important for the understanding of Alzheimer's disease development, generates amyloid beta (Ab)-like peptides, toxic protein fragments from the amyloid precursor protein that are considered...
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