Forever Young: Scientists Have Discovered RNA That Doesn’t Age in the Brain

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Forever Young: Scientists Have Discovered RNA That Doesn’t Age in the Brain
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Science, Space and Technology News 2024

Scientists have found that certain RNA molecules in brain cells, termed long-lived RNAs, can persist throughout an organism’s life, playing a critical role in maintaining genome stability and offering insights into brain aging and potential therapies for neurodegenerative diseases.molecules in the nerve cells in the brain last a life time without being renewed.

In order to determine the life span of the RNA molecules, the Toda group worked together with the team from Prof. Dr. Martin Hetzer, a cell biologist at the Institute of Science and Technology Austria . “We succeeded in marking the RNAs with fluorescent molecules and tracking their lifespan in mice brain cells,” explains Tomohisa Toda, who has unique expertise in epigenetics and neurobiology and who was awarded an ERC Consolidator Grant for his research in 2023.

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