Police in Florida, announced that they had dismantled a drug trafficking operation in the area, leading to about 15 arrests.
and other experts in the field still recommend naloxone be given, because there are few side effects to an unnecessary dose of the reversal medication and xylazine is usually taken alongside an opioid like fentanyl.
"The naloxone will still work on everything that's an opioid," said Anita Jacobson, a pharmacist and clinical professor at the University of Rhode Island College of Pharmacy,."Any opioid will be reversed, and breathing will be restored, but they may still be sedated, because xylazine is a sedative and its effects are not reversed. Responding to an overdose has changed in that regard. People may not wake up when they're given naloxone, but it will restore their breathing.
Xylazine can also cause complications like bedsores, from being asleep in one place too long, and injuries, from falling unexpectedly. The most alarming complication, and one referenced by Blanford, is wounds on users' bodies. Alixe Dittmore, a training and content development coordinator with the National Harm Reduction Coalition who provides direct care to people who use drugs,that these wounds often appear on injection sites or on limbs. The wounds are not like abscesses, which are common among injection drug users, but instead resemble blisters that open and expand, leading to a risk of infection and often growing wider instead of deeper. The wounds can become necrotic and in some cases lead to soft tissue injury.
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