Omega-3 supplements do not reduce fractures in healthy seniors: VITAL ASBMR2022
Omega-3 supplements did not reduce fractures during a median 5.3-year follow-up in the more than 25,000 generally healthy men and women in theThe large randomized controlled trial tested whether omega-3 fatty acid or vitamin D supplements prevented cardiovascular disease or cancer in a representative sample of midlife and older adults from 50 US states — which they did not.
However, these subgroup findings need to be interpreted with caution and may be due to chance, LeBoff warned. The researchers will be investigating these findings in further analyses.Asked whether, in the meantime, patients should start or keep taking supplements for possible health benefits, she noted that certain individuals might benefit.
The current study tells us that,"so far, we haven't been able to demonstrate a reduced rate of fractures with fish oil supplements in clinical randomized trials" conducted in relatively healthy and not the oldest patients, she summarized."We're not talking about 80-year-olds," she noted. Preclinical studies have shown that omega-3 fatty acids reduce bone resorption and have anti-inflammatory effects, but observational studies have reported conflicting findings.VITAL enrolled a national sample of 25,871 US men and women, including 5106 Black participants, with a mean age of 67 and a mean BMI of 28 kg/mImportantly, participants were not recruited by low bone density, fractures, or vitamin D deficiency.
Participants in the omega-3 fatty acid and placebo groups had similar baseline characteristics. For example, about half were women, and on average, they ate 1.1 servings of dark-meat fish per week.Plasma omega-3 levels were measured at baseline and, in 1583 participants, at 1 year of follow-up. The mean omega-3 index rose 54.7% in the omega-3 fatty acid group and changed < 2% in the placebo group at 1 year.
After excluding digit, skull, and pathologic fractures, there was no significant reduction in total fractures , nonvertebral fractures , or hip fractures , with omega-3 supplements versus placebo.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Apple iOS 15.7: Unprecedented iPhone Update Focuses On 11 Vital Security FixesTwo software updates in one day? That’s a first. Read on for what’s been released and how to choose between this and iOS 16.
Read more »
Watch: With the salmon collapse on the Yukon River, families are losing a vital food source and way of lifeSubsistence fishing for king and chum salmon has been closed on the Yukon River for two summers due to record low runs. Residents are now facing food insecurity and a devastating loss of culture because of the collapse.
Read more »
Jean-Luc Godard, iconic French New Wave director, dies at 91Jean-Luc Godard stood for years as one of the most vital and provocative directors in Europe and beyond — beginning in 1960 with his debut feature “Breathless.”
Read more »
Bitcoin's Health May Hinge on a Legal Feud in NorwaySome $BTC developers say a lawsuit from pseudonymous bitcoiner Hodlonaut against Craig Wright, who claims to be Satoshi Nakamoto, is vital to the cryptocurrency’s growth. mehmehturtle reports
Read more »
Jewher Ilham Is Dismantling The Politics Of Fashion And Forced Labor'It is possible now to make ethical choices when shopping, but I’m fighting for a future when the ethical choice is the only one we have.'
Read more »