The JAK inhibitor's safety profile for patients as young as 2 years was similar to known to the known safety profile in adults.
Upadacitinib is now indicated for patients aged 2 years or older with active polyarticular juvenile idiopathic arthritis and psoriatic arthritis who cannot tolerate or achieve adequate disease response with one or more tumor necrosis factor blockers, according to a
"Pediatric patients with pJIA and PsA can be severely limited in their ability to complete daily physical tasks and participate in everyday activities. Understanding their needs today and knowing the likelihood of disease in adulthood underscores the need for additional treatment options," Aarat Patel, MD, a pediatric rheumatologist at Bon Secours Rheumatology Center, Richmond, Virginia, said in the press release.
Juvenile Ra Juvenile Idiopathic Arthritis Children Child Childhood Pediatrics Kids Jak/Stat Jak-Stat Signaling Pathway Jak-Stat Cytokine Receptors Psoriatic Arthritis Arthropathic Psoriasis Psoriatic Arthropathy Psa Ankylosing Spondylitis Rheumatoid Spondylitis Rheumatoid Arthritis Of The Spine Bechterew's Disease Bechterew Syndrome
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