XBB 1.5 is the dominant strain now circulating, with 40% of new cases having this strain, according to the U.S. Centers for Disease Control and Prevention. About 18% of new cases have XBB.1.16 and 12.5% have XBB 1.9.1.
FDA scientists said redesigned boosters should target at least one variant of XBB, according to briefing documents published Monday.“These data suggest that an updated strain composition ofto more closely match currently circulating omicron sublineages is warranted for the 2023-2024 vaccination campaign,” the scientists wrote.
The World Health Organization and the European Medicines Agency have both said a booster should target an XBB subvariant.have evolved, from a shot in December 2020 that targeted the original virus to FDA-approved shots last fall that targeted the original COVID strain as well as the omicron subvariants BA.4 and BA.5.
XBB 1.5 is the dominant strain now circulating, with 40% of new cases having this strain, according to the U.S. Centers for Disease Control andCurrent boosters provide some protection against XBB 1.5, but not as much as for BA.4 and BA.5. The FDA's Advisory Committee on Immunization Practices, which will decide who should get a booster, will also meet next week to talk about this and otherIt would make sense if the COVID boosters were offered to everyone in the fall, Dr. Ofer Levy, director of the Precision“In my mind, it seems like a logical framework,” said Levy, a member of the FDA's advisory committee who will be involved in Thursday's meeting.
A new booster could be either bivalent, like last year's, targeting two strains or monovalent, targeting just that which is most prevalent.
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