A study in the Journal of Headache and Pain finds a bidirectional relationship between insomnia and pain localized in the head, neck/shoulder, back, and hip regions. It supports existence of causal relationships between localized pain and mental disorders.
, the predispositions of several localized pains are significantly associated with the risk of sleeplessness/insomnia and depression. Headaches , neck/shoulder pain , back pain , and hip pain are significant factors predisposing to sleeplessness/insomnia. Headaches , neck/shoulder pain , back pain , stomach/abdominal pain , and knee pain are significant contributors to depression.The putative causal effect of localized pain on mental disorders.
It is worth noting that the absence of any pain is associated with significantly lower genetic susceptibility of sleeplessness/insomnia , anxiety/panic attacks and depression . Detailed MR results of localized pain on the risk of mental disorders with scatter plots can be found in supplementary fileReverse directional MR revealed a significant causal relationship between mental disorders and several localized pain . Sleeplessness/insomnia increases the genetic susceptibility of pain in all sites, including headache , facial pain , neck/shoulder pain , back pain , stomach/abdominal pain , hip pain , and knee pain .
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