NIH scientists find that IV administration improves tumor-fighting action. An experimental therapeutic cancer vaccine induced two distinct and desirable immune system responses that led to significant tumor regression in mice. This is according to a new research study published in the journal Cell,
Scientists found that IV administration of the vaccine boosted the number of cytotoxic T cells capable of infiltrating and attacking tumor cells and engaged the innate immune system by inducing type I interferon.An experimental therapeutic cancer vaccine induced two distinct and desirable immune system responses that led to significant tumor regression in mice.
According to the research findings, intravenous administration of the vaccine boosted the number of cytotoxic T cells capable of infiltrating and attacking tumor cells and engaged the innate immune system by inducing type I interferon. The innate immune response modified the tumor microenvironment, counteracting suppressive forces that otherwise would tamp down T-cell action.
SNAPvax, the name of the experimental vaccine, was designed by Robert Seder, M.D., and colleagues at the NIAID Vaccine Research Center together with collaborators from Vaccitech North America, a clinical-stage biopharmaceutical company in Baltimore, Maryland. Vaccitech announced plans to advance the SNAPvax platform for use in treating human papillomavirus associated cancer in 2023.T cells and remodels the tumor microenvironment” by Faezzah Baharom, Ramiro A.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
Hope for a breast cancer vaccine growsAn experimental vaccine may be able to prevent or treat a particularly aggressive form of breast cancer, according to findings from a new study.
Read more »
New NIH Study Suggests That a Heart Medication Reduces Alcohol ConsumptionThe medication could potentially treat alcohol use disorder. A recent study by National Institutes of Health researchers and their colleagues suggests that a medication used to treat heart issues and high blood pressure may also be useful in treating alcohol use disorder. The study presents converg
Read more »
U.S. Supreme Court's Sotomayor rejects challenge to N.Y. COVID vaccine mandate(Reuters) -U.S. Supreme Court Justice Sonia Sotomayor on Thursday rejected a bid to prevent New York City from enforcing its COVID-19 vaccine mandate for municipal workers against a group teachers, firefighters and others who challenged the policy. The justice denied an emergency request, received by the court on Nov. 4, to block the policy by individual municipal workers, as well as a group called New Yorkers For Religious Liberty, while their appeal of lower court decisions siding with the city proceeds. The plaintiffs - firefighters, building inspectors, police officers, emergency medical technicians, teachers, sanitation workers and others - are represented by the Alliance Defending Freedom conservative religious liberty group.
Read more »
Justice Sonia Sotomayor declines to block NYC public sector Covid-19 vaccine mandate | CNN PoliticsJustice Sonia Sotomayor on Thursday rejected a request that the Supreme Court block New York City's public sector Covid-19 vaccine requirement as it applies to employees with who have religious objections to the vaccine.
Read more »
Arlington County To Close Public COVID-19 Vaccine ClinicArlington County will close its public vaccine clinic along with most of its COVID-19 testing blocks before the end of the year, stating that 'Demand has significantly decreased at the county’s clinic.'
Read more »