A recent study suggests that people taking the GLP-1 liraglutide experienced more bone loss than people who exercised during the same time period. However, the study also found that exercising while taking liraglutide and other GLP-s may help prevent bone loss.
Brian is a New York–based science and health journalist. His work has been published by The Atlantic, The Paris Review, The New York Times For Kids, CBS News, The TODAY Show, Barron's PENTA, Engadget, and Healthline, among others.Nick Blackmer is a librarian, fact-checker, and researcher with more than 20 years of experience in consumer-facing health and wellness content.
Prior to this study, combining these medications with exercise had "not been investigated in the context of bone health," she said.For the study, the researchers performed a “secondary analysis” of a randomized clinical trial conducted from August 2016 to November 2019 at the University of Copenhagen and Hvidovre Hospital in Denmark.
The researchers found that those taking liraglutide had more bone loss than those in the exercise group, despite similar weight loss. Participants in the combination exercise-GLP-1 group experienced the most weight loss, but their bone mineral density levels remained similar to those not taking the medication.
For one, the study focused on people younger than 65 and those without chronic health issues, like diabetes, so the results may not apply to these groups.
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