Researchers evaluated outcomes for 351 melanoma in situ lesions in 294 patients in a retrospective study.
in situ on low-risk body sites that was managed with 5-mm margins had a local recurrence rate of 0.9%, results from a retrospective case series from a single dermatology practice in Australia showed. This approach has the potential to reduce morbidity and cost associated with treatment"without compromising patient outcomes in a selected population of lesions," the authors say.
The mean age of patients was 60.3 years, 55.5% were female, and the mean dimensions of the lesions was 6 × 5 mm. The most common subtype of melanoma diagnosed was superficial spreading melanoma , followed bymaligna and lentiginous MIS . Nearly half of the lesions were on the trunk , followed by the upper limb , lower limb , neck , face , and scalp . As for the size of lesions, 78.1% were < 10 mm long and 88.9% were < 10 mm wide.
Only three of the 351 lesions had a local recurrence, with no regional recurrence or metastatic spread, and 99.1% had no recurrence. The recurrences were reexcised"with clear margins" and after at least 5 years of follow-up, no further recurrences were reported, the authors said. studies, reported recurrence rates for MIS have been"between 0.26% and 1.1%, with excisional margins between 6 and 12 mm required," the authors noted."This study demonstrated a comparable 0.
Malignant Skin Neoplasm Melanoma Malignant Melanoma Mohs Surgery Mohs Micrographic Surgery Biopsy Limbs Surgery Torso Cancer Malignant Neoplasia Carcinoma Malignant Neoplasm Neck Cervical Region Of Neck Clinical Guidelines Guidelines Facial Hospitals Lentigo Scalp
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