Evaluating dual direct-acting antivirals against persistent COVID-19 researchsquare GSTTnhs COVID19 SARSCoV2 Antivirals
By Bhavana KunkalikarNov 7 2022Reviewed by Aimee Molineux In a recent study posted to the Research Square* preprint server, researchers assessed the efficiency of dual direct-acting antivirals in treating persistent coronavirus disease 2019 .
This report describes a 60-year-old man who experienced COVID-19 symptoms on 25 April 2022 and had a positive lateral flow test. He initially tested SARS-CoV-2-positive in April 2022 and was hospitalized four times due to COVID-19 symptoms. From August 2020, he had consistent, bimonthly monotherapy with obinutuzumab while in remission. Before testing positive, he was vaccinated with four COVID-19 vaccine doses.
-G. He was administered sotrovimab , pulsed methylprednisolone , and remdesivir for another five days. He was discharged while with ambulatory oxygen and continued usage of prednisolone . Admission four: day 96 to day 145 Soon after being discharged, the fever returned, and the shortness of breath worsened, necessitating readmission. The previous pulmonary embolism was found to be resolved on the CT of the thorax. Additionally, ground-glass opacification had grown in extent and density and was beginning to resemble acute respiratory distress syndrome in appearance. There was no overt fibrosis detected.
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