New ESC guidelines recommend using both an SGLT2 inhibitor and a GLP-1 receptor agonist simultaneously to treat people with type 2 diabetes and established cardiovascular disease.
based on a depressed estimated glomerular filtration rate and an elevated urine albumin-to-creatinine ratio.
The guidelines also, for the first time for ESC recommendations, made treatment with finerenone a class 1 level A recommendation for people with type 2 diabetes and CKD.Another major change in the new ESC guideline revision is introduction of a CVD risk calculator intended to estimate the risk among people with type 2 diabetes but without established CVD, heart failure, or CKD.
Key features of the calculator include its use of routinely collected clinical values, such as age, sex, systolic blood pressure, smoking status, serum cholesterol levels, age at diabetes diagnosis, hemoglobin A"For the first time we have a clear score to categorize risk" in people with type 2 diabetes and identify who needs more aggressive treatment to prevent CVD development," said Emanuele Di Angelantonio, MD, PhD, Deputy Director of the Cardiovascular Epidemiology Unit at the...
"The risk score is a good addition" because it estimates future CVD risk better and more systematically than usual practice, which generally relies on no systematic tool, said Naveed Sattar, PhD, professor of metabolic medicine at the University of Glasgow, United Kingdom, and also a member of the guideline-writing panel.
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