How do complex mixtures of chemicals affect our health? New research has shown that chemicals that occur in complex mixtures and in concentration ratios as found in humans act together. Even if the concentrations of the individual substances were each below the effect threshold, the chemicals in the mixture showed a cumulative neurotoxic effect.
Chemicals are omnipresent today: they enter our bodies through food, air or the skin. But how do these complex mixtures of chemicals affect our health? In a study published in the journal, a research team from the Helmholtz Centre for Environmental Research has shown that chemicals that occur in complex mixtures and in concentration ratios as found in humans act together.
The extensive research work was based on over 600 blood samples from pregnant women from the Leipzig mother-child cohort LiNA, which has been coordinated by the UFZ since 2006. The researchers first analysed the individual mixtures of chemicals present in these samples."We wanted to find out which chemicals were contained in the blood plasma and in what concentrations.
But what exactly do these results mean?"With our study, we were able to prove for the first time that what is known about the effects of chemical mixtures in the environment also applies to humans," says Escher."It is therefore imperative that we rethink risk assessment. Indicator substances alone are far from sufficient. In future, we must learn to think in terms of mixtures.
Georg Braun, Gunda Herberth, Martin Krauss, Maria König, Niklas Wojtysiak, Ana C. Zenclussen, Beate I. Escher.The very first life on earth is thought to have developed from 'protocells' -- liquid mixtures of many different types of molecules. Researchers have now shown that in such mixtures, small ...
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