Early 49ers vs Bills Predictions, Picks, and Odds for SNF Week 13

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Early 49ers vs Bills Predictions, Picks, and Odds for SNF Week 13
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Our Early 49ers vs. Bills predictions expect Buffalo to wipe the floor with San Francisco on SNF.

The Buffalo Bills have one of the most potent offenses in the NFL, and they're about to open a can of whoop ass vs. a depleted Niners squad.Sunday Night Football’s showdown between the San Francisco 49ers and Buffalo Bills was supposed to be a possible Super Bowl preview in Week 13.

On top of Purdy’s unknown status, the 49ers have a laundry list of ailments on the offensive line as well as the defense. Those injuries are compounded by a schedule that squeezes San Francisco, which plays back-to-back road games and its third away tilt in four weeks.are refreshed and ready for the stretch run after enjoying a Week 12 bye. The Bills just earned a resume victory over Kansas City in Week 11 and extended their winning streak to six games.

Also playing into this dropping number is the forecast in Orchard Park. Sunday night could see snow flurries at Highmark Stadium, with some weather models calling for temperatures to “feel like” 12 degrees with wind gusts getting up to 20 mph. The Bills’ offense is expecting to have pieces back in the receiving corps, with WR Keon Coleman and TE Dalton Kincaid trending toward a Week 13 return.

Since joining the Covers team back in 2005, he’s honed his handicapping skills to provide audiences with the most thorough insights, blending traditional capping methods with advanced modelling and predictive analysis. Jason has studied the ins and outs of the sports betting business, learning from some of the most successful gamblers in the industry and the biggest sportsbook operators on the planet.

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