In the relentless battle against antibiotic-resistant superbugs, science continues to unveil ingenious strategies to address their vulnerability. Like other bacteria, superbugs have a unique weakness—their dependence on iron for growth and survival. Iron serves as an essential nutrient that bacteria utilize for various cellular processes, including DNA replication, energy production, and other vital functions. In essence, iron is like a 'food' for bacteria.
Antimicrobial resistance in bacterial infections has emerged as a significant global health concern. The overuse and misuse of existing antibiotics have accelerated the acquired drug resistance in bacteria, resulting in resistance to almost all antibiotics used in clinical settings across various bacteria strains.
Gram-negative bacteria, including Pseudomonas aeruginosa, can cause a range of infections in humans. These infections often affect the respiratory system, leading to pneumonia or lung infections, as well as urinary tract infections. They can also lead to skin and soft tissue infections, bloodstream infections , and infections in wounds or surgical sites.
Although the frequency of resistance of P. aeruginosa to cefiderocol is much lower than its parent antibiotic ceftazidime, the resistance to cefiderocol was developed inevitably in several Gram-negative bacteria strains recently, for example, in Carbapenem-resistant Escherichia coli strains and Acinetobacter baumannii in burned infections.
United States Latest News, United States Headlines
Similar News:You can also read news stories similar to this one that we have collected from other news sources.
‘Memory’ Director Talks Indie Film Amid Dual Strikes: “We’re Hoping This Makes Us Stronger”With Jessica Chastain and Peter Sarsgaard at his side for a North American premiere, Mexican auteur Michel Franco said he was “lucky” to have his lead actors on stage at TIFF.
Read more »
Hollywood's janitors swept out of jobs by dual strikesYolanda Cendejas was let go from her job as a studio janitor on May 5, days after Hollywood writers went on strike, leaving the Los Angeles resident without income and the health insurance she needs to cover treatment for her diabetes.
Read more »
Bronc rider at West Texas rodeo killed after getting bucked off horseA bronc rider was killed over the weekend after falling off a horse at a rodeo in West Texas.
Read more »
Probe fails to pinpoint reason for horse deaths at Churchill DownsHorse racing watchdog group investigation finds no ‘singular explanation’ for recent cluster of horse deaths at Churchill Downs.
Read more »